R-404A
R-404A is a non-ozone-depleting replacement for R-502 and R-22 used in commercial refrigerator equipment for low and medium temperature ranges.

What is R-404A?
R-404A is a blend of R-125, R-143a, and R-134a, designed for medium and low-temperature refrigeration applications. It is widely used in commercial refrigeration systems, including supermarkets, cold storage, and transport refrigeration. R-404A provides excellent cooling performance but operates at higher pressures compared to older refrigerants like R-22.
Systems designed for R-404A are optimized to handle these pressures and utilize POE (Polyolester) lubricants to ensure compatibility. While retrofitting older systems for R-404A use is possible with proper modifications, professional consultation is strongly recommended to maintain efficiency and reliability. Known for its energy efficiency and performance under demanding conditions, R-404A is classified as non-toxic and non-flammable, meeting the A1 safety standard. However, as part of the global phase-down of HFCs, R-404A is being gradually replaced with lower-GWP alternatives for more sustainable operation.
Important Note

Key Properties of R-404A
Low Boiling Point
Boils at (1 atm, °F): -51.8, making it efficient for heat transfer in cold storage and transport refrigeration.
High Pressure Operation
Operates at higher pressures than R-22, requiring specially designed equipment.
Improved Energy Efficiency
Offers better energy efficiency compared to older refrigerants like R-22.
Zero Ozone Depletion
Has an Ozone Depletion Potential (ODP) of 0, making it safer for the environment.
Global Warming Potential
Has a GWP of 3920, which is significant but lower than some alternatives.
Non-Flammable
Classified as A1 (lowest toxicity, no flame propagation) by ASHRAE.
Technical Specifications
Applications and Usage
Residential Systems
- Limited use due to its focus on commercial and industrial refrigeration applications
Commercial Applications
- Supermarket refrigeration systems
- Convenience store display cases
- Ice machines
Industrial Applications
- Cold storage warehouses
- Food processing plants
- Transport refrigeration systems (e.g., refrigerated trucks and containers)
Specialized Uses
- Medical refrigeration equipment
- Laboratory-grade cooling systems
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