R-407A
R-407A is a non-ozone-depleting replacement for R-404A and R-507 in system designs or from existing R-22 refrigeration units.

What is R-407A?
R-407A (a blend of R-32, R-125, and R-134a) is a hydrofluorocarbon (HFC) refrigerant designed as a replacement for R-22 and R-404A in medium and low-temperature refrigeration systems. Known for its efficient cooling properties, R-407A provides improved energy performance while reducing the environmental impact compared to R-22.
R-407A requires synthetic lubricants, such as polyolester (POE) oils, for compatibility and operates at pressures similar to R-404A, ensuring reliable performance across various commercial and industrial applications. While its global warming potential (GWP) is lower than R-404A, it remains higher than newer HFO blends, making it a practical transitional refrigerant for systems unable to adopt advanced alternatives.
Important Note

Key Properties of R-407A
Low Boiling Point
Boils at (1 atm, °F): -49.9, making it efficient for medium and low-temperature refrigeration systems.
High Pressure Operation
Operates at higher pressures than R-22, requiring specially designed equipment.
Improved Energy Efficiency
Offers better energy efficiency compared to older refrigerants like R-22.
Zero Ozone Depletion
Has an Ozone Depletion Potential (ODP) of 0, making it safer for the environment.
Global Warming Potential
Has a GWP of 2110, which is significant but lower than some alternatives.
Non-Flammable
Classified as A1 (lowest toxicity, no flame propagation) by ASHRAE.
Technical Specifications
Applications and Usage
Residential Systems
- Retrofitted residential air conditioning systems originally designed for R-22
- Limited use in small-scale cooling appliances requiring medium or low-temperature performance
Commercial Applications
- Supermarket refrigeration systems replacing R-404A or R-22
- Packaged rooftop HVAC units retrofitted for medium-temperature cooling
- Beverage display coolers, freezers, and ice machines in commercial environments
Industrial Applications
- Cold storage facilities transitioning from R-22 or R-404A
- Food processing refrigeration units requiring reliable medium and low-temperature performance
- Industrial cooling systems supporting manufacturing and logistics operations
Specialized Uses
- Medical-grade refrigeration systems retrofitted from R-22
- Laboratory cooling systems requiring a lower-GWP alternative to R-404A
- Systems needing compliance with modern refrigerant regulations while maintaining efficiency
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