R-422D
R-422D is a non-ozone-depleting, multi-purpose refrigerant that works in existing low and medium temperature direct expansion refrigeration applications, including commercial supermarket systems.

What is R-422D?
R-422D (a blend of R-125, R-134a, and R-600a) is a hydrofluorocarbon (HFC) refrigerant designed as a replacement for R-22 in existing refrigeration and air conditioning systems. Unlike R-422B, which is better suited for smaller residential and light commercial systems, R-422D is particularly optimized for medium and low-temperature commercial and industrial applications. It offers compatibility with both traditional mineral oil (MO) and alkylbenzene (AB) lubricants, simplifying retrofits by minimizing the need for major system modifications
R-422D operates at pressures comparable to R-22, delivering reliable performance and efficiency for larger-scale refrigeration systems transitioning away from ozone-depleting refrigerants. While it has a higher global warming potential (GWP) than newer alternatives, it remains a practical and cost-effective solution for industrial cooling systems, cold storage, food processing facilities, and similar demanding environments where advanced options may not be viable. Classified as non-toxic and non-flammable under the A1 safety rating, R-422D provides a robust option for applications requiring durability and efficiency under challenging conditions.
Important Note

Key Properties of R-422D
Low Boiling Point
Boils at (1 atm, °F): -45.8, making it efficient for medium and low-temperature commercial and industrial applications.
Low Pressure Operation
Operates at slightly lower pressures than R-22, requiring similar but retrofitted equipment or none at all.
Similar Energy Efficiency
Offers similar energy efficiency compared to older refrigerants like R-22, but 0 ODP.
Zero Ozone Depletion
Has an Ozone Depletion Potential (ODP) of 0, making it safer for the environment.
Global Warming Potential
Has a GWP of 2730, which is significant but lower than some alternatives.
Non-Flammable
Classified as A1 (lowest toxicity, no flame propagation) by ASHRAE.
Technical Specifications
Applications and Usage
Residential Systems
- Limited use in residential settings, primarily for retrofitted air conditioning systems originally designed for R-22
- Small-scale cooling units requiring medium or low-temperature performance
Commercial Applications
- Medium and low-temperature refrigeration systems in supermarkets and convenience stores
- Packaged rooftop HVAC units retrofitted from R-22
- Beverage display coolers, freezers, and ice machines in commercial settings
Industrial Applications
- Large-scale cold storage facilities retrofitted from R-22 systems
- Food processing refrigeration units requiring reliable, medium, and low-temperature cooling
- Industrial cooling systems used in manufacturing and logistics sectors
Specialized Uses
- Medical-grade refrigeration equipment retrofitted from R-22 systems
- Laboratory cooling systems requiring a non-ozone-depleting alternative to R-22
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